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大多数分化型甲状腺癌(DTC)分化良好,复发及转移率低,预后较好,但部分亚型分化不良,容易复发并发生局部及远处转移,死亡率较高。大量研究表明血清Tg水平可作为监测分化型甲状腺癌术后复发及转移的特异性指标。由于各种良、恶性甲状腺疾病都可导致血清Tg水平升高,以往认为术前监测血清Tg水平的意义不大,但近年来越来越多的研究表明,术前血清Tg水平的监测也具有重要的临床价值。本文旨在对近年来关于甲状腺球蛋白(Tg)在DTC术前及术后诊疗过程中的应用进展进行综述。
Most differentiated thyroid cancer (DTC) well-differentiated, low recurrence and metastasis, the prognosis is good, but some subtypes poorly differentiated, easy to relapse and the occurrence of local and distant metastasis, higher mortality. A large number of studies have shown that serum Tg can be used as a specific indicator to monitor the recurrence and metastasis of differentiated thyroid cancer. As a variety of benign and malignant thyroid diseases can lead to elevated serum Tg, in the past that preoperative serum Tg level of little significance, but in recent years, more and more studies have shown that preoperative serum Tg level monitoring also has Important clinical value. This article aims to summarize recent advances in the application of thyroglobulin (Tg) in DTC preoperative and postoperative diagnosis and treatment.