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目的:观察中药辅助治疗Graves病并发急性心肌损害的效果。方法:将Graves病并发急性心肌损害患者120例根据入院病床单双号分为治疗组与对照组各60例。对照组给予放射131碘结合盐酸乐卡地平治疗;治疗组在对照组治疗的基础上给予熟地龙骨汤治疗,治疗周期为1周。结果:总有效率治疗组为90.0%,对照组为70.0%,两组比较,差异有统计学意义(P<0.05)。两组治疗前EDV、ESV、EF与SV值比较,差异无统计学意义(P>0.05),两组治疗后EDV与ESV值均降低,两组治疗后比较,治疗组EDV与ESV均低于对照组,差异有统计学意义(P<0.05)。治疗后随访3个月,两组的恶心呕吐、皮疹、脑血管疾病、疲劳等并发症比较,差异无统计学意义(P<0.05)。结论:熟地龙骨汤辅助治疗Graves病并发急性心肌损害能提高疗效,有效改善左心室功能,同时安全性也较好。
Objective: To observe the effect of traditional Chinese medicine adjuvant treatment of Graves’ disease complicated by acute myocardial damage. Methods: One hundred and twenty cases of Graves’ disease complicated with acute myocardial damage were divided into treatment group and control group according to single and double numbers of hospitalized bed respectively. The control group was treated with radioactive 131 iodine combined with lercanidipine hydrochloride. The treatment group was treated with the fortified Keel Keel Decoction on the basis of the control group, and the treatment cycle was 1 week. Results: The total effective rate was 90.0% in the treatment group and 70.0% in the control group. There was significant difference between the two groups (P <0.05). There was no significant difference in EDV, ESV, EF and SV between the two groups before treatment (P> 0.05). EDV and ESV decreased after treatment in both groups. EDV and ESV in the two groups after treatment were lower than those in the treatment group Control group, the difference was statistically significant (P <0.05). The patients were followed up for 3 months after treatment. The comparisons of nausea, vomiting, rash, cerebrovascular disease and fatigue in the two groups showed no significant difference (P <0.05). Conclusion: Rehmannia decoction assisted Graves’ disease with acute myocardial damage can improve the curative effect, effectively improve left ventricular function, and also have better safety.