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目的探讨高温和噪声等飞行环境对飞行员红细胞膜脂质过氧化的影响。方法用分光光度计法测定２４ 名飞行员，飞行前（ 早晨６ 时） 、飞行后即刻（ 中午１２ 时） 以及飞行后８ ｈ（ 晚上２０ 时） 的红细胞膜谷胱甘肽过氧化物酶（ＧＳＨｐｘ） 及丙二醛（ ＭＤＡ） 的含量，并与对照组（２１ 名地面普通人员） 进行比较。结果飞行后即刻红细胞膜中的谷胱甘肽过氧化物酶活力明显低于对照组，飞行后即刻和飞行后８ ｈ 的丙二醛含量明显高于普通地面人员。结论高温和噪声等飞行环境可导致飞行员红细胞膜脂质过氧化反应增强和抗氧化能力降低。
Objective To investigate the effects of high temperature and noise on the erythrocyte membrane lipid peroxidation in pilots. Methods 24 pilots, pre-flight (at 6:00), post-flight (12 noon) and post-flight 8 h (20:00) erythrocyte membrane glutathione peroxidase (GSHpx) were measured by spectrophotometer. ) And malondialdehyde (MDA) were measured and compared with the control group (21 ground level personnel). Results The glutathione peroxidase activity of erythrocyte membrane immediately after flight was significantly lower than that of the control group. The content of malondialdehyde immediately after flight and 8 h after flight was significantly higher than that of ordinary ground staff. Conclusion The flight environment such as high temperature and noise can lead to the enhancement of lipid peroxidation and the decrease of anti-oxidation ability of pilots erythrocyte membrane.