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目的:探讨口服中毒患者洗胃治疗后血清电解质异常发病的相关因素。方法:回顾分析我院2015-06-2016-12收治的给予清水洗胃的147例中毒患者临床资料。结果:洗胃后血清电解质异常的发病率为71.43%,其中钾离子37.41%、钠离子26.53%、氯离子23.81%、钙离子27.89%。147例中毒患者的28d病死率为42.18%,死亡组和存活组患者白细胞计数、中性粒细胞计数、血红蛋白、血清钾离子浓度、尿素氮、肌酐比较差异有统计学意义(P<0.05),其中死亡组中重度低钾血症的发病率(29.03%)大于存活组(4.71%)。洗胃液量(GV)<20L组血清钾离子浓度大于GV≥20L组(P<0.05)。结论:中毒患者洗胃后较易发生血清电解质的异常,以血清钾离子最为多见,尤其在GV≥20L时。
Objective: To investigate the related factors of abnormal serum electrolytes after gastric lavage treatment in oral poisoning patients. Methods: A retrospective analysis of our hospital 2015-06-20-16-12 admitted to the lavage of patients with clinical data of 147 cases of poisoning. Results: The incidence of abnormal serum electrolytes after gastric lavage was 71.43%, of which 37.41% were potassium, 26.53% sodium, 23.81% chloride and 27.89% calcium. 147 cases of poisoning patients 28d mortality was 42.18%, white blood cell count, neutrophil count, hemoglobin, serum potassium concentration, urea nitrogen and creatinine in death group and survival group were significantly different (P <0.05) Among them, the incidence of severe hypokalemia in the death group (29.03%) was higher than that in the survival group (4.71%). Gastric potassium concentration in gastric lavage fluid (GV) <20L group was greater than that in GV≥20L group (P <0.05). Conclusion: In patients with poisoning, serum electrolyte abnormalities are more likely to occur after gastric lavage. Serum potassium ion is most common, especially when GV≥20L.