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目的分析河北省食管癌高发区磁县、涉县29年(1974~2002年)上消化道恶性肿瘤的死亡情况,为肿瘤防治提供依据。方法对比分析磁县、涉县同时期20世纪70年代(1974~1976年)、90年代(1990~1992年)、21世纪初(2000~2002年)全人群肿瘤登记的食管癌、贲门癌、非贲门胃癌的死亡率。结果自20世纪70年代到21世纪初,磁县、涉县食管癌粗死率均呈现明显下降趋势,磁县食管癌粗死率下降了40.96/10万,下降了32.21%;而同时期涉县下降了65.74/10万,下降了50.06%。磁县贲门癌和非贲门胃癌的粗死率呈现曲线波动,变化不大,20世纪70年代贲门癌死亡占上消化道恶性肿瘤死亡的5.67%,到90年代占4.58%,21世纪初占8.15%。而涉县贲门癌呈现明显上升趋势,非贲门胃癌呈现明显下降趋势,发现贲门癌在上消化道恶性肿瘤死亡中所占比重越来越大,由20世纪70年代的6.28%上升到新世纪的30.17%。磁县、涉县人群中男性贲门癌的死亡率高于女性。磁县山区贲门癌死亡率高于丘陵和平原,年平均死亡率达到11.61/10万,且有上升趋势。结论29年来磁县、涉县食管癌死亡呈显著下降趋势,磁县贲门癌、非贲门胃癌死亡均呈曲线波动;涉县贲门癌死亡率呈明显上升趋势,非贲门胃癌死亡率呈下降趋势。
Objective To analyze the death of upper gastrointestinal cancer in Cixian County and Shexian County in the high incidence area of esophageal cancer in Hebei Province for 29 years (from 1974 to 2002), so as to provide evidence for the prevention and treatment of cancer. Methods A comparative analysis was made between the esophageal and cardia cancers registered in the entire population in Cixian and Shexian during the same period of the 1970s (1974-1976), 1990s (1990-1992), and early 2000s (2000-2002) Non-cardiac gastric cancer mortality. Results From the 1970s to the beginning of the 21st century, the crude fatality rate of esophageal cancer in Cixian County and Xianxian County showed a significant decrease. The crude fatality rate of Esophageal cancer in Cixian County dropped by 40.96 / 100000, down by 32.21%; while in the same period The county dropped 65.74 / 100,000, down 50.06%. The death rate of cardia cancer and non-cardia gastric cancer in Ci County fluctuated with little change. In the 1970s, the death of cardia cancer accounted for 5.67% of the deaths of upper gastrointestinal malignancies, up to 4.58% in the 1990s and 8.15% in the early 21st century %. Cardia cancer in Shexian County showed a significant upward trend, non-cardia gastric cancer showed a significant downward trend and found that cardia cancer in the proportion of upper gastrointestinal cancer deaths more and more from 6.28% in the 1970s rose to the new century 30.17%. Cixian, Shexian population male cardia cancer mortality higher than women. Cixian mountainous area cardia cancer mortality higher than the hills and plains, the annual average mortality rate reached 11.61 / 100,000, and an upward trend. Conclusion The mortality of esophageal cancer in Cixian county and Coxian county decreased significantly in 29 years. The mortality of cardia cancer and non-cardia gastric cancer showed a curve fluctuation in Cixian County. The mortality rate of cardia cancer in Shexian County increased significantly, and the mortality rate of non-cardia gastric cancer showed a decreasing trend.