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目的探讨六神曲中微生物、消化酶的检测状况及对神曲质量控制的意义。方法依据文献资料,分析六神曲中微生物及消化酶的检测手段及研究现状。结果与结论六神曲中微生物及消化酶的检测均侧重于终点控制,动态测定较少,发酵过程中微生物、消化酶及组方药物间的相互作用有待深入研究。加强神曲这一复杂系统的整体性、动态性、相关性研究,可为探寻神曲组方机理,优化发酵工艺,建立量化质控标准提供有益借鉴。
Objective To explore the status of detection of microorganisms and digestive enzymes in Liushen Qu and its significance on quality control of Divine Comedy. Methods Based on the literature data, the detection methods and research status of microorganisms and digestive enzymes in Liushen song were analyzed. RESULTS AND CONCLUSIONS The detection of microorganisms and digestive enzymes in Liushen song focuses on the end point control with less dynamic determination. The interaction between microorganisms, digestive enzymes and prescription drugs needs to be further studied in the fermentation process. Enhancing the complex, holistic, dynamic and relativity research of Divine Comedy can provide a beneficial reference for exploring Divine Comedy prescription mechanism, optimizing fermentation process and establishing quantitative quality control standards.