精子减少与精子活力不足为不育症的常见原因,至今还缺少满意的治疗方法。氯菧酚曾被广泛应用,有人认为用低剂量时效果良好,有人则认为效果不稳定,可能由于氯菧酚含有抗雌激素与雌激素双重作用。所以仅含有抗雌激素作用的顺式氯菧酚的治疗效果较优。Tamoxifen为一抗雌激素制剂,其内在的雌激素作用较氯菧酚低得多,因此作者试用于80例精子减少与精子活力不足的病例中,选择对象为患不育症至少一年以上;精子活力不足的标准是:射精后活力≤50%,3小时后活力≤30%;精子减少的标准是计数低于40×10~6/ml(60 Sperm loss and lack of sperm motility is a common cause of infertility, so far still lack of satisfactory treatment. Chlorophenol has been widely used, some people think that the effect is good with low doses, while others think the effect is not stable, probably due to chlorophenol containing anti-estrogen and estrogen dual role. So only contains the role of anti-estrogen cis-chlorophenol better treatment. Tamoxifen, an antiestrogen, has a much lower intrinsic estrogenic effect than chlorphenols, so the authors tested 80 cases of sperm depletion and insufficient sperm motility with at least one year of infertility. Sperm The criteria for lack of vitality are: ≤50% viability after ejaculation, ≤30% viability after 3 hours; and the standard for reduction of sperm count is less than 40 × 10 ~ 6 / ml