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近年来由于抗生素、皮质类固醇等药物的广泛应用,白色念珠菌病(白念)较为常见,患者有所增加。目前临床应用的抗真菌药物主要为多烯抗生素、氨基甲酸酯及咪唑类等。这些药物疗效肯定,但存在一些毒副反应,理想的药物极少。因而急待开发疗效高,毒副作用小的新型药物。中草药具有悠久的历史,从中开发抗真菌药物已进行大量的筛选工作,并取得一定的进展。本文概述有关抗白念方面的研究结果。
In recent years, due to the widespread use of antibiotics, corticosteroids and other drugs, white candidiasis (white candida) is more common and patients have increased. The current clinical antifungal drugs mainly include polyene antibiotics, carbamates and imidazoles. The efficacy of these drugs is certain, but there are some toxic side effects, and ideal drugs are few. Therefore, it is urgent to develop new drugs with high curative effect and small side effects. Chinese herbal medicine has a long history, and a lot of screening work has been carried out for the development of antifungal drugs, and certain progress has been made. This article outlines the results of studies on anti-whitening.