2型糖尿病不同于1型糖尿病,是一种遗传易感性疾病,尽管对其特异的多态性或突变认识尚不清楚,但对其影响肝脏、骨骼肌、脂肪、β细胞或大脑的生理机制已将陆续得到阐明,但大多数研究者认为遗传因素对胰岛素抵抗、胰岛素分泌缺陷存在着影响[1-2],更多学者更倾向影响胰岛素抵抗在前,β细胞功能伤害则多发生在抵抗后阶段[3]。当然环境因素也起着作用,甚至是更重要的作用,所以称为易感性。1 2型糖尿病发生、发展的一般过程严格说来,胰岛素 Type 2 diabetes, unlike type 1 diabetes, is a predisposing disorder that is not known for its specific polymorphisms or mutations but affects its physiological mechanisms in the liver, skeletal muscle, fat, beta cells, or brain Has been gradually clarified, but most researchers believe that genetic factors have an impact on insulin resistance, insulin secretion defects [1-2], more scholars tend to affect insulin resistance in the former, β-cell function damage occurs in the resistance After the stage [3]. Of course, environmental factors also play a role, and even more important role, so called susceptibility. 1 Type 2 diabetes occurs, the general process of development Strictly speaking, insulin