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银杏叶提取物(EGb761)可明显延长双侧颈总动脉结扎导致的急性脑缺血小鼠的存活时间,显著降低小鼠脑缺血再灌期脑组织谷胱甘肽过氧化物酶和钠钾ATP酶活性的抑制。预先给予EGb761可减轻海马缺血再灌后的亚细胞结构损伤。
Ginkgo biloba extract (EGb761) can significantly prolong the survival time of mice with acute cerebral ischemia caused by ligation of bilateral common carotid arteries, and significantly reduce brain glutathione peroxidase and sodium in cerebral ischemia-reperfusion mice. Potassium ATPase activity inhibition. Pre-administration of EGb761 reduced the damage of subcellular structure after hippocampal ischemia and reperfusion.