流行病学调查和实验研究确认,高热量、高脂肪膳食与大肠癌的发生密切相关,大肠癌高发国家多为高脂肪膳食。实验证明,高脂肪膳食组比低脂肪组发癌率高。究其原因,一是高脂肪食物本身大多含胆固醇高;二是高脂肪食物进入胃肠道后需要分泌较多的胆汁进行消化,胆汁的主要成分胆酸,其来源和化学结构都与胆固醇有密切的关系。研究人员测定了粪便中胆酸含量发现,大肠癌患者、高脂肪膳食者粪便中的胆酸含量比 Epidemiological investigation and experimental studies confirmed that high-calorie, high-fat diet and the occurrence of colorectal cancer are closely related to the high incidence of colorectal cancer are mostly high-fat diet. Experiments show that high-fat diet group than low-fat group cancer rate. The reason, first, most of the high-fat foods contain high cholesterol; second, high-fat foods into the gastrointestinal tract need to secrete more bile for digestion, the main component of bile acid, its source and chemical structure with cholesterol close relationship. Researchers measured the fecal bile acid content found in colorectal cancer, high-fat diet in the stool of bile acids than