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目的:探析产前彩超筛查对孕中期先天性心脏病(FCHD)-复杂畸形胎儿的临床诊断意义。方法:分析2011年1月~2013年1月在我院接受产前彩超筛查的848例孕中期妇女(观察组)的临床资料。比较胎儿心脏彩超检查结果与产后的随访结果、尸解结果以及新生儿彩超检查结果。结果:848例孕中期妇女中共检出26例FCHD-复杂畸形胎儿,其检出率为3.1%。与产后随访结果相比,彩超筛查对大动脉转位、心内膜垫缺损等的检出率无显著性差异;有5例漏诊(0.6%),其中2例室间隔缺损、2例合并心外畸形,1例法洛四联症。产前超声筛查结果与尸解结果、新生儿彩超检查结果间均无统计学差异。结论:产前彩超筛查对孕中期FCHD-复杂畸形胎儿的检出率较高,可以使此类新生儿的出生率得到显著降低,有助于优生优育政策的落实。
Objective: To explore the significance of prenatal color Doppler ultrasonography in the diagnosis of congenital heart disease (FCHD) complex fetus. Methods: The clinical data of 848 pregnant women (observation group) receiving prenatal screening in our hospital from January 2011 to January 2013 were analyzed. Comparison of Fetal Heart Color Doppler ultrasound examination results and postpartum follow-up results, autopsy results and neonatal ultrasound results. Results: Totally 26 fetuses with FCHD-complex deformity were detected in 848 pregnant women of middle-stage pregnancy. The detection rate was 3.1%. Compared with the results of postpartum follow-up, there was no significant difference in the detection rate of transposition of aorta and endocardial pad defect among the 5 cases (0.6%), of which 2 cases were ventricular septal defect and 2 cases were complicated with heart External deformity, one case of tetralogy of Fallot. Prenatal ultrasound screening results and autopsy results, neonatal ultrasonography showed no significant difference between the results. Conclusion: The prenatal screening of FCHD-complex fetal malformations higher detection rate of fetal fetuses in the second trimester can make the birth rate of these newborns was significantly reduced, is conducive to the implementation of prenatal and postnatal care policy.