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[目的]探讨恶性肿瘤合并血栓栓塞性疾病的特点。[方法]回顾性分析22例经病理学证实的恶性肿瘤合并血栓栓塞性疾病患者的临床资料。[结果]22例恶性肿瘤合并血栓栓塞性疾病中,并发颈内静脉血栓形成4例,单纯下肢深静脉血栓形成(DVT)10例,单纯肺血栓栓塞(PTE)3例,DVT合并PTE5例。5例合并PTE患者中3例有较典型的临床症状,多有低氧血症、血D-二聚体明显升高。心电图仅1例有典型SIQIIITIII表现。[结论]恶性肿瘤并发血栓栓塞性疾病临床常见,对手术、化疗、放疗、PICC置管或疾病进展可能导致血液高凝状态患者应及早进行抗凝治疗,预防血栓栓塞性疾病的发生。
[Objective] To investigate the characteristics of malignant tumor complicated with thromboembolism. [Methods] The clinical data of 22 patients with pathologically confirmed malignant tumor complicated with thromboembolic diseases were retrospectively analyzed. [Results] Among the 22 cases of malignant tumor complicated with thromboembolic diseases, 4 cases were complicated by internal jugular vein thrombosis, 10 cases were simple deep vein thrombosis (DVT), 3 cases were simple pulmonary thromboembolism (PTE) and 5 cases were DVT complicated with PTE. Among the 5 patients with PTE, 3 patients had typical clinical symptoms, more hypoxemia and increased blood D-dimer. Only one of the electrocardiogram showed typical SIQIIITIII performance. [Conclusion] Thromboembolic diseases are common in malignant tumors. Surgery, chemotherapy, radiotherapy, PICC catheter or disease progression may lead to anticoagulant therapy in patients with hypercoagulable state of blood and prevention of thromboembolic diseases.