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目的了解肥城矿区1～59岁人群乙型肝炎病毒(HBV)感染现状,评价实施乙肝疫苗免疫效果,为制定预防控制策略提供依据。方法按照整群随机抽样方法 ,调查1～59岁人群共1803人,进行乙肝血清流行病学调查,并用酶联免疫吸附试验(ELISA)方法检测乙肝病毒表面抗原(HBsAg)、乙肝病毒表面抗体(抗-HBs)、乙肝病毒核心抗体(抗-HBc)。结果肥城矿区调查人群HBsAg、抗-HBs、抗-HBc、HBV感染率分别为1.99%、56.96%、16.41%和26.46%,乙肝疫苗接种率达到60.45%。结论肥城矿区人群乙肝病毒感染率已降至较低水平,实施乙肝疫苗免疫接种取得良好效果,接种乙肝疫苗是控制人群HBV感染的有效措施。
Objective To understand the status of hepatitis B virus (HBV) infection in 1-59-year-old population in Feicheng mining area and evaluate the effect of hepatitis B vaccine in order to provide evidence for the prevention and control strategies. Methods A total of 1803 people aged 1-59 years were enrolled in this study. According to the randomized sampling method, the serological epidemiology of hepatitis B was investigated. The levels of HBsAg and HBsAg were detected by enzyme-linked immunosorbent assay (ELISA) Anti-HBs), hepatitis B virus core antibody (anti-HBc). Results The prevalence rates of HBsAg, anti-HBs, anti-HBc and HBV among the surveyed population in Feicheng mine area were 1.99%, 56.96%, 16.41% and 26.46% respectively, and the hepatitis B vaccination rate reached 60.45%. Conclusion Hepatitis B virus infection rate in Feicheng mining area has been reduced to a low level. The hepatitis B vaccine immunization has achieved good results. Hepatitis B vaccine is an effective measure to control HBV infection in the population.