论文部分内容阅读
目的:通过对肝硬化失代偿者检测凝血四项、D-二聚体及PLT,以探讨在肝硬化病变中的意义。方法:肝硬化失代偿者98例,健康对照21例,均检测PT、APTT、TT、FIB、D-二聚体及PLT,并进行统计分析。结果:肝硬化失代偿者随病情加重PT、APTT、TT、D-D不同程度增高;FIB及PLT则降低。差异均有统计学意义(P<0.05或P<0.01)。结论:肝硬化失代偿者凝血及纤溶机制存在明显异常,与肝硬化程度密切相关。
OBJECTIVE: To detect clotting four, D-dimer and PLT in patients with decompensated cirrhosis to explore the significance in the pathogenesis of cirrhosis. Methods: 98 cases of decompensated liver cirrhosis and 21 healthy controls were detected PT, APTT, TT, FIB, D-dimer and PLT, and statistical analysis. Results: The degree of PT, APTT, TT and D-D in patients with decompensated liver cirrhosis increased with different degrees of exacerbations; FIB and PLT decreased. The differences were statistically significant (P <0.05 or P <0.01). Conclusion: The mechanism of coagulation and fibrinolysis in patients with decompensated cirrhosis is obviously abnormal, which is closely related to the degree of cirrhosis.