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取慢性肺原性心脏病(肺心病)急性加重期10例,做口服葡萄糖耐量试验(OGTT),并测定应激性激素及胰岛素(Ins)。选健康人10例作对照。结果表明:肺心病急性加重期血清皮质醇、FT_4、HGH分泌增加,Ins分泌增加,血糖升高,显示Ins抵抗,机体对糖的利用减低。而胰高糖素分泌正常并未参与该病的应激过程。说明该病在急性加重期宜适当限制糖的摄入,皮质激素也并非必需常规使用。
Take 10 cases of chronic pulmonary heart disease (pulmonary heart disease) acute exacerbation period, oral glucose tolerance test (OGTT), and determination of stress hormones and insulin (Ins). 10 healthy people were selected as control. The results showed that the secretion of serum cortisol, FT_4 and HGH increased, the secretion of Ins increased and the blood sugar increased in the acute exacerbation stage of pulmonary heart disease, which showed that Ins was resistant and the utilization of carbohydrate was reduced. The normal secretion of glucagon did not participate in the stress of the disease process. That the disease in the exacerbation should be appropriate to limit sugar intake, corticosteroids are not necessarily routine use.