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目的观察酚妥拉明静滴联合布地奈德雾化吸入治疗毛细支气管炎的临床疗效。方法将96例毛细支气管炎患儿随机分为两组,对照组48例,采用常规抗感染、拍背、吸痰治疗;治疗组48例,在对照组治疗的基础上加用酚妥拉明0.5 mg/(kg.次),加入5%葡萄糖50 ml,按酚妥拉明4～6μg/(kg.min)静脉泵入,同时布地奈德按1 mg/次以空气压缩泵汽雾吸入。并对临床疗效、住院天数和安全性进行比较。结果两组相比,治疗组的主要症状缓解时间及住院时间明显短于对照组,差异有统计学意义(P<0.05),但两组治愈率比较差异无统计学意义(P>0.05)。未见明显不良反应。结论布地奈德联合酚妥拉明治疗毛细支气管炎,能尽快缓解患儿喘憋症状,减少住院天数,效果显著,安全可靠,值得临床推广。
Objective To observe the clinical efficacy of phentolamine combined with budesonide inhalation in the treatment of bronchiolitis. Methods 96 cases of children with bronchiolitis were randomly divided into two groups, the control group of 48 cases, using conventional anti-infection, shoot back, suction sputum treatment; 48 cases in the control group based on the treatment with phentolamine 0.5 mg / (kg. Times), 50 ml of 5% glucose was added, and phentolamine 4 ~ 6 μg / (kg.min) was pumped intravenously. Budesonide was inhaled by 1 mg / . Clinical efficacy, hospitalization days and safety were compared. Results Compared with the two groups, the main symptom relief time and hospitalization time in the treatment group were significantly shorter than those in the control group (P <0.05). However, there was no significant difference in the cure rate between the two groups (P> 0.05). No obvious adverse reactions. Conclusion Budesonide combined with phentolamine treatment of bronchiolitis, as soon as possible to relieve symptoms of wheezing in children with reduced hospitalization days, the effect is significant, safe and reliable, it is worth clinical promotion.