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目的:分析和探讨纳洛酮联合中药治疗急性酒精中毒的临床疗效,总结其临床价值。方法:回顾性分析2012年6月至2013年6月来我院就诊的急性酒精中毒患者40例,分为观察组和对照组两组,每组患者有20例。两组患者均给予持续心电监护、保暖、吸氧等措施,尽快建立静脉通道。给予5%的葡萄糖进行补液,给予利尿、护肝,以及维持水电解质酸碱平衡等措施。对照组患者给予纳洛酮进行治疗,观察组患者在对照组治疗的基础上联合使用中药醒脑静注射液进行治疗,分析和比较两组不同治疗方法的临床效果。结果:按以下制定的标准评价治疗急性酒精中毒的临床效果。对照组治愈6例,有效8例,无效6例,总有效率为70.00%,观察组治愈9例,有效9例,无效2例,总有效率为90.00%,经检验,对照组和观察组两组不同治疗方法的临床疗效具有显著差异(p<0.05),观察组疗效优于对照组。结论:采用纳洛酮联合中药醒脑静治疗急性酒精中毒具有较好的临床效果,值得临床借鉴和推广。
Objective: To analyze and explore the clinical efficacy of naloxone combined with traditional Chinese medicine in the treatment of acute alcoholism and to summarize its clinical value. Methods: A retrospective analysis of 40 patients with acute alcoholism who came to our hospital from June 2012 to June 2013 was divided into observation group and control group, with 20 patients in each group. Two groups of patients were given continuous ECG monitoring, warmth, oxygen and other measures to establish venous access as soon as possible. Give 5% glucose for rehydration, giving diuretic, liver protection, and maintain water and electrolyte acid-base balance and other measures. The patients in the control group were treated with naloxone. The patients in the observation group were treated with the combination of Chinese herbal medicine Xingnaojing injection on the basis of the control group. The clinical effects of two groups of different treatment methods were analyzed and compared. Results: The clinical efficacy of treatment of acute alcoholism was evaluated according to the following criteria. In the control group, 6 cases were cured, 8 cases were effective and 6 cases were ineffective. The total effective rate was 70.00%. In the observation group, 9 cases were cured, 9 cases were effective and 2 cases were ineffective. The total effective rate was 90.00% The two groups of different treatment methods have significant clinical efficacy (p <0.05), the observation group than the control group. Conclusion: Naloxone combined with Xingnaojing in the treatment of acute alcoholism has a good clinical effect, which deserves clinical reference and promotion.