应用放射免疫法测定18例不同病因引起的肾功能损害及24例正常人的血清肌红蛋白(SMb)浓度。结果发现肾功能损害者均有SMb水平升高,即使肌酐轻度升高者,其SMb值比正常人也显著升高(P<0.001)。提示检测SMb对肾功能损害者有诊断价值。此外,在临床应用SMb测定对其他疾病作出诊断前,首先必须排除肾功能损害。 Radioimmunoassay was used to determine the renal damage caused by different etiologies and serum concentration of myoglobin (SMb) in 24 healthy individuals. The results showed that renal dysfunction were SMb levels were elevated, even slightly elevated creatinine SMb value was significantly higher than normal (P <0.001). Prompt detection of SMb on the diagnosis of renal dysfunction have diagnostic value. In addition, prior to the clinical application of the SMb assay for the diagnosis of other diseases, first of all, renal function impairment must be ruled out.