论文部分内容阅读
目的:探讨CAG方案初治老年急性髓系白血病的疗效。方法:Ara-C 25 mg/(m2.d),每隔12 h 1次,第1~14天;阿克拉霉素10 mg/(m2.d),第1~7天;G-CSF的剂量为200μg/(m2.d),皮下注射,在小剂量Ara-C前注射。结果:20例经化疗后完全缓解9例,部分缓解4例,总有效率65%,13例中FAB分类M2a7例,M5a4例,M5b型2例。结论:预激方案初治老年急性髓系白血病疗效较好,不良反应轻,尤其对高龄、并发症多、对强化疗不能耐受的患者更为适用。
Objective: To investigate the curative effect of CAG regimen on newly diagnosed senile acute myeloid leukemia. Methods: Ara-C 25 mg / (m2.d) every 12 h for 1 to 14 days; aclacinomycin 10 mg / (m2.d) for days 1 to 7; Dose 200μg / (m2.d), subcutaneous injection, in small doses of Ara-C before injection. Results: In the 20 cases, 9 cases were completely relieved after chemotherapy, 4 cases partially relieved, and the total effective rate was 65%. Among 13 cases, 7 cases were FAB classification M2a, 4 cases M5a and 2 cases M5b. Conclusion: The pre-shock regimen is effective in treating newly diagnosed acute myeloid leukemia in elderly patients with mild adverse reactions, especially for elderly patients with more complications and more refractory to intensive chemotherapy.