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目的观察地奥司明片在胫骨干骨折术后水肿的临床疗效。方法122例患者被分为治疗组62例，对照组60例，治疗组口服地奥司明片2片/次,3次/d口服，连服10d。对照组每天快速静点20%甘露醇注射液125ml 2次/d连用10d。结果治疗3、6、10d后治疗组和对照组两组患者下肢消肿情况,治疗组疗效更显著。两组比较差异均有统计学意义。(<0.05)。结论地奥司明片治疗胫骨干骨折术后水肿疗效满意。“,”Objective To observe the clinical ef ects of daflon in treatment of edema after operation for tibial diaphyseal fracture. Methods The 122 patients were divided into treatment group (62cases)and control group(60cases).Treatment group received daflon oral y 2 pieces each time(0.45g per piece)three time a day for ten day.The other patients in control group received rapid.Intravenous dripping of 20%Mannitol injection 125ml,bid for ten days.Results After 3,6,10 days,The regression of lower extremity edema of treatment group were significantly bet er than that of control group.There were statistical y dif erence between the two groups( <0.05).Conclusion The clinicai ef ects of daflon in treatment of edema after operation for tibial diaphyseal fracture were satisfactory.