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为探讨老年人听觉功能个体差异的病理生理学基础，本文以耳蜗电图和听性脑干反应同时记录的方法，对１０２名（２０４耳）健康老年人（４５～８１岁）进行了测试。我们发现老年前期老年聋组较老年前期听力正常组Ⅲ～Ⅴ间期显著延长（Ｐ＜００１），耳蜗电图ＡＰ（Ｎ１）潜伏期无显著改变（Ｐ＞００５）；老年期老年聋的中重度聋组较轻度聋组Ⅰ～Ⅲ、Ⅰ～Ⅴ间期显著延长（Ｐ＜００５），而ＡＰ（Ｎ１）潜伏期无显著改变（Ｐ＞００５）。结果提示老年人听觉功能的个体差异无论从老年聋是否发生，还是从耳聋程度的差异来看，主要是由于听觉中枢退化程度的不同所致。因此，预防和治疗对中枢神经系统有显著影响的一些老年性疾病，将对预防和延缓老年聋的发生和发展有重要意义。
In order to explore the pathophysiology of individual differences in auditory function in the elderly, 102 (204 ears) healthy elderly (45-81 years old) were tested by the simultaneous recording of cochlear electrogram and auditory brainstem response. We found that the presenile senile deaf group had significantly longer duration of Ⅲ ~ Ⅴ period (P <001) and no significant change of latency (P> 005) in auditory cochlear electrocautery AP (N1> 0) The deafness of moderate to severe deaf group mild to severe deaf group Ⅰ ~ Ⅲ, Ⅰ ~ Ⅴ interval was significantly prolonged (P <005), while the AP (N1) latency was not significantly changed (P> 005). The results suggest that individual differences in auditory function of the elderly are not only caused by senile deafness but also deafness, mainly due to the different degrees of degeneration of the auditory center. Therefore, prevention and treatment of some elderly diseases that have a significant impact on the central nervous system will play an important role in preventing and delaying the occurrence and development of senile deafness.