一氧化氮 (NO)作为神经递质或调质已经确定。一氧化氮合酶 (NOS)活性在大鼠不同脑区的定位是本文研究的重点。采用 NADPHd酶组织化学方法 ,对大鼠海马、脑干内 NOS的活性进行观察。结果显示 :海马 (CA1 ～ CA3区 ) NOS为阳性 (+)、其中 CA2 为强阳性 ( ) ;非脑神经核 (红核、黑质 )为中等阳性 ( ) ;而脑神经核 (动眼神经核、动眼神经副核、面神经核、展神经核 ) NOS为阳性 (+) ;脑桥网状结构为阳性 (+) ;缝核群为阳性 (+) ;第三脑室和第四脑室脉络丛为阳性 (+)。 Nitric oxide (NO) has been identified as a neurotransmitter or quencher. The localization of nitric oxide synthase (NOS) activity in different brain regions of rats is the focus of this study. The NADPHd enzyme histochemical method was used to observe the activity of NOS in the hippocampus and brainstem of rats. The results showed that NOS in the hippocampus (CA1 ~ CA3 area) was positive (+), of which CA2 was strongly positive (P <0.05). The non-cranial nucleus Nucleus, oculomotor nucleus, facial nucleus, optic nerve nucleus) positive for NOS (+); positive for pontine reticular structure (+); positive for karyotypic nucleus (+); third ventricle and fourth ventricle choroid plexus Positive (+).