动物肾实质组织的减少,发生进行性氮血症、蛋白尿、肾小球硬化是由于残肾肾小球毛细血管静水压及血流量增加,引起每个功能肾单位的小球滤过率增加,从而导致肾小球损害。Iucchclli等报告了单肾切除术后的病人亦按顺序发生蛋白尿、高血压、肾衰。Davison等描述了单肾切除术后局灶性肾小球硬化机会增多。本实验研究了27名自幼切除单肾的病人, The reduction of animal renal parenchyma, the occurrence of progressive azotemia, proteinuria, glomerulosclerosis is due to residual renal glomerular capillary hydrostatic pressure and increased blood flow, causing each functional unit of the ball of renal filtration rate Increased, resulting in glomerular damage. Iucchclli et al reported that patients who underwent nephrectomy also had proteinuria, hypertension, and renal failure in sequence. Davison et al describe an increased chance of focal glomerulosclerosis after nephrectomy. This experiment studied 27 young single kidneys patients,