高氟暴露可导致机体多系统、多脏器损伤。近年来 ,高氟暴露对机体免疫功能影响的研究取得较大进展 ,其研究主要集中在细胞免疫、体液免疫、细胞因子等三方面。本文就此作一综述 High fluoride exposure can cause multiple body systems and multiple organ damage. In recent years, the research on the impact of high fluoride exposure on the immune function has made great progress. The research mainly focuses on three aspects: cellular immunity, humoral immunity and cytokines. This article gives a summary of this