目的:建立胃复康胶囊的质量标准。方法:以十八烷基硅烷键合硅胶为填充剂,采用C18(250mm×4.6mm,5μm)色谱柱,流动相为甲醇-0.1%磷酸溶液(三乙胺调PH值至6.0,55∶45),检测波长为280nm。结果:胃复康胶囊中浙贝母、甘草、枳壳薄层色谱中,在与对照药材色谱相应的位置上,显相同颜色的斑点;延胡索乙素0.128~0.768μg范围内线性关系良好,平均回收率为96.76%,RSD为1.24%,平均每粒胃康胶囊中含延胡索乙素0.384mg/g。结论:经试验,确定本方法准确可行,操作简便,可做本品的质量控制。 Objective: To establish the quality standard of Weifukang capsule. Methods: C18 (250mm × 4.6mm, 5μm) column with octadecylsilane bonded silica as mobile phase was used. The mobile phase consisted of methanol - 0.1% phosphoric acid solution (triethylamine adjusted to pH 6.0 and 55:45 ), Detection wavelength of 280nm. Results: In FFA capsule, Fritillaria thunbergii, Licorice root and Fructus aurantii thin layer chromatogram showed the same color spots at the position corresponding to the reference drug chromatogram. The linear range of 0.128 ~ 0.768 μg of tetrahydropalmatine was good, the average The recovery rate was 96.76%, RSD was 1.24%, with an average of 0.384 mg / g tetrahydropalmatine per capsule. Conclusion: After testing, this method is accurate and feasible, easy to operate, can do the quality control of this product.