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目的探讨低分子肝素钙联合葛根素治疗不稳定型心绞痛的方法和疗效。方法对45例不稳定型心绞痛患者,在常规治疗心绞痛的基础上应用低分子肝素钙5 000 U皮下注射,葛根素针0.6 g加入5%葡萄糖或生理盐水250～500 m l中静脉滴注,用药前后对比观察血液流变学、心电图及心绞痛发作次数及程度。结果45例不稳定型心绞痛患者治疗总有效率为93.33%,其中显效55.56%,心电图改善率84.44%,其中显效46.66%;45例出凝血指标都延长,但无临床出血等并发症。结论低分子肝素钙联合葛根素治疗不稳定型心绞痛疗效好,安全性高。
Objective To investigate the method and effect of low molecular weight heparin combined with puerarin in the treatment of unstable angina pectoris. Methods 45 patients with unstable angina pectoris were treated with subcutaneous injection of low molecular weight heparin 5000 U on the basis of conventional treatment of angina pectoris, 0.6 g of puerarin was added into 5% dextrose or normal saline 250 ~ 500 ml intravenously, Contrast before and after observation of hemorheology, electrocardiogram and angina pectoris frequency and extent. Results The total effective rate of 45 cases of unstable angina pectoris was 93.33%, 55.56% of them were markedly improved, the improvement rate of electrocardiogram was 84.44%, 46.66% of them were markedly improved. The coagulation indexes of 45 cases were prolonged without complication of clinical bleeding. Conclusion Low molecular weight heparin combined with puerarin in the treatment of unstable angina pectoris has good efficacy and high safety.