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探讨骨髓间充质干细胞移植调节心肌梗死后免疫炎症反应。急性心肌梗死往往伴随强烈的免疫炎症反应。近来研究表明,骨髓间充质干细胞具有免疫炎症调节作用,移植到体内后可以调节免疫炎症反应,可以延缓心肌梗死后心室重塑。现就心肌梗死后免疫炎症反应及骨髓间充质干细胞移植后调节免疫炎症反应做一简要综述。
To investigate bone marrow mesenchymal stem cell transplantation to modulate immune inflammation after myocardial infarction. Acute myocardial infarction is often accompanied by a strong immune inflammation. Recent studies have shown that bone marrow mesenchymal stem cells have immunomodulatory effects, which can regulate immune and inflammatory responses after transplantation into the body and delay post-MI ventricular remodeling. Now on post-myocardial infarction immune inflammation and bone marrow-derived mesenchymal stem cell transplantation to regulate immunoinflammatory reaction to do a brief review.