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目的探讨分析阿奇霉素联合特步他林雾化吸入治疗小儿支原体肺炎疾病的临床疗效。方法 90例小儿支原体肺炎疾病患儿,随机分为对照组和研究组,各45例。对照组给予红霉素+小儿咳喘灵常规治疗,研究组给予阿奇霉素+特步他林雾化吸入治疗,观察两组患儿治疗状况,并对比分析。结果研究组不良反应总发生率为8.89%低于对照组的31.11%,差异有统计学意义(P<0.05)。治疗后,研究组患儿小气道功能指数(MEF25、MEF50、MEF25-75)分别为(2.6±0.4)、(3.0±0.4)、(2.9±0.9)L/s高于对照组的(1.2±0.4)、(1.8±0.4)、(1.1±0.2)L/s,差异有统计学意义(P<0.05)。研究组咳嗽、喘憋、肺部啰音消失时间以及胸片恢复正常时间分别为(4.3±1.9)、(3.2±1.2)、(4.2±1.6)、(8.6±3.2)d均短于对照组的(6.9±2.1)、(5.4±1.2)、(7.1±2.2)、(12.2±3.3)d,差异有统计学意义(P<0.05)。结论临床治疗小儿支原体肺炎疾病可考虑把阿奇霉素+特步他林雾化吸入方式纳入到首选方式中进行选择,疗效佳,促进各症状消失,降低不良反应,存在进一步推广性。
Objective To investigate the clinical efficacy of azithromycin combined with tebutrine inhalation in the treatment of mycoplasma pneumonia in children. Methods Ninety children with mycoplasma pneumonia were randomly divided into control group and study group, with 45 cases each. The control group was given erythromycin + pediatric Kechuanling routine treatment, the study group was given azithromycin + Xteptazin aerosol inhalation treatment, the treatment of children in both groups were observed and compared. Results The total incidence of adverse reactions in the study group was 8.89%, which was lower than that in the control group (31.11%) (P <0.05). After treatment, the small airway function index (MEF25, MEF50, MEF25-75) of the study group were (2.6 ± 0.4), (3.0 ± 0.4) and (2.9 ± 0.9) L / 0.4), (1.8 ± 0.4) and (1.1 ± 0.2) L / s respectively. The difference was statistically significant (P <0.05). The duration of cough, wheezing, disappearance of pulmonary rales and normal time of chest radiography in study group were (4.3 ± 1.9), (3.2 ± 1.2), (4.2 ± 1.6) and (8.6 ± 3.2) days, respectively, which were shorter than those in control group (6.9 ± 2.1), (5.4 ± 1.2), (7.1 ± 2.2), (12.2 ± 3.3) d, respectively. The difference was statistically significant (P <0.05). Conclusion The clinical treatment of children with mycoplasma pneumonia disease can be considered azithromycin + Xtepralin inhalation into the preferred method of choice, good effect, and promote the disappearance of symptoms, reduce adverse reactions, there is further promotion.