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目的:对比分析多潘立酮与铝碳酸镁两种药物治疗胆汁反流性胃炎的效果。方法:选择该院收治治疗的100例胆汁反流性胃炎患者,按照临床用药方案的不同,进行实验组和参照组组别划分,其中实验组行多潘立酮治疗,参照组行铝碳酸镁治疗。对比两组胆汁反流性胃炎的效果以及药物毒副反应等。结果:经比较,两组胆汁反流性胃炎患者治疗后,其总有效率、不良反应发生率比,没有明显差别P>0.05。对两组患者治疗前后24 h胆汁检测结果(反流总时间、次数、最长反流时间以及5 min以上反流持续发生次数等)比较,治疗后均优于治疗前,P<0.05。结论:对胆汁反流性胃炎患者来说,采用多潘立酮与铝碳酸镁进行治疗效果显著,且两种药物使用所得效果无明显差异,都可以作为临床治疗推荐药物。
Objective: To compare the effects of domperidone and aluminum magnesium carbonate in the treatment of bile reflux gastritis. Methods: 100 cases of bile reflux gastritis treated in our hospital were selected. According to the different clinical regimens, the experimental group and the reference group were divided into groups. The experimental group received domperidone and the reference group received aluminum magnesium carbonate. Compare the effect of two groups of bile reflux gastritis and drug side effects. Results: After comparing the two groups of patients with bile reflux gastritis after treatment, the total effective rate, the incidence of adverse reactions, there was no significant difference P> 0.05. The results of bile test (total reflux time, number of times, longest reflux time and the number of reflux recurrence more than 5 minutes) before and 24 h after treatment were significantly better than those before treatment (P <0.05). Conclusion: For patients with bile reflux gastritis, the treatment with domperidone and aluminum magnesium carbonate has a significant effect, and there is no significant difference between the two drugs. All of them can be used as recommended drugs for clinical treatment.