患者男,52岁,以间断腹泻1年四肢、口周及肛周皮疹伴精神症状2余天入院。患者于1年前因其妻服毒自杀后出现精神不佳,大量饮酒,每日饮白酒1~1.5kg,很少进食,约1个月后出现腹泻,为黏液便,每日4~5次偶有脓血便,自服消炎药物后可缓解至此次发病前患者持续大量饮酒。近20d来患者双手 Male, 52 years old, with intermittent diarrhea 1 year limbs, perioral and perianal rashes with psychiatric symptoms more than 2 days admission. 1 year ago, his wife took poison after taking suicide, he developed mental retardation and consumed a lot of alcohol. He drank 1 to 1.5 kg of white wine a day, rarely eating and diarrhea after about 1 month. It was mucus, 4 to 5 times a day Occasionally pus and blood will, since the anti-inflammatory drugs can ease the onset of the patient continued to drink a lot. Nearly 20d patients hands