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Objective: To study the cellular immunity status of patients with recurrent genital herpes.Methods: Serum levels of interlukin-2 and its soluble receptor and interlukin-6 were measured by ELISA in 34patients with recurrent genital herpes.Results: Serum levels of IL-2 and IL-6 were significantlydecreased in patients compared to healthy controls (P＜0.01),and the level of sIL-2R was significantly increased in patientswith recurrent genital herpes (P＜0.01). There were nosignificant differences in all variables amongst patientsregarding relapse stage and remission stage (P ＞0.05).Conclusion: There was a cellular immune deficiency inpatients with recurrent genital herpes.