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【目的】探讨慢性化脓性中耳炎(Chronic suppurative otitis media ,CSOM )患者手术前后生活质量及其影响因素。【方法】选取2010年5月至2015年5月于本院行手术治疗的CSOM患者216例,采用慢性化脓性中耳炎生活质量量表(CSOM‐QOL)及视觉模拟量表(VAS)评价其手术前后生活质量及分析其影响因素。【结果】与手术前相比,患者手术后生活质量总评分、躯体表现、情感异常、医学资源利用、日常活动受限制评分明显较高;患者手术后平均VAS评分显著低于手术前;手术前患者中,年轻、生活在城市、累及双耳、鼓膜穿孔的患者生活质量总评分较低( P <00.5);手术后患者中,累及双耳、鼓膜穿孔的患者生活质量总评分较高(P <00.5)。患者手术前年龄、生活环境、累及耳别、中耳炎类型与生活质量有相关性(P <00.5);手术后累及耳别、中耳炎类型与生活质量有相关性( P <00.5)。【结论】CSOM 患者经手术治疗后生活质量明显改善,累及双耳及病情较严重的患者术后生活质量改善更加明显,可根据生活质量评价选择合适的治疗手段。“,”[Objective]To explore the quality of life and its influence factors in patients with chronic sup‐purative otitis media before and after operation .[Methods]Two hundred and sixteen patients with chronic sup‐purative otitis media underwent operation in our hospital from May 2010 to May 2015 were selected .Quality of life and its influence factors of patients before and after operation were evaluated by the scale of quality of life for chronic suppurative otitis media (CSOM‐QOL)and the visual analog scale(VAS) .[Results]Compared with the situation before operation ,patients had significantly higher scores in total quality of life ,somatic manifes‐tations ,affective disorders ,medical resource utilization and restricted daily activities after operation .The av‐erage VAS score of patients after operation was significantly lower than that before operation .Among the pre‐operative patients ,those with young age who lived in the city and involved in the two ears and the ear drum perforation got a lower score in the total quality of life ( P <0 0.5);Age ,living environment ,involvement of the ear ,and the types of otitis media before surgery were correlated with the quality of life ( P <0 0.5);the types of the ear involved after surgery and otitis media were associated with the quality of life ( P <0 .05) .[Conclusion] The quality of life of patients with chronic suppurative otitis media have been improved signifi‐cantly after operation ,especially in those involved in the two ears complicated with severe symptoms .Thus , an appropriate treatment may be adopted and performed according to the evaluation of quality of life .