红霉素作为大环内酯类代表药物常用于临床 ,由于其胃肠道副反应往往使患者不易耐受 ,限制了该药的应用。我们应用思密达消除和减轻红霉素胃肠道副反应取得良好效果 ,现报告如下。1　临床资料1995年 5月～ 1999年 12月 ,因患下呼吸道感染而住院患儿 2 4 0例 ,其中男 99例 ,女 14 Erythromycin is commonly used as a representative of macrolide drugs in clinical practice, which limits its application due to its gastrointestinal adverse reactions are often difficult to tolerate. We use Smectite to eliminate and alleviate the gastrointestinal side effects of erythromycin achieved good results, are as follows. 1 Clinical data May 1995 ~ December 1999, hospitalized children suffering from lower respiratory tract infection 240 cases, of which 99 were male and female 14