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在速发型变态反应(第一型变态反应)过程中,由于过敏介质的释放,引起皮疹、皮炎、荨麻疹、支气管哮喘、胃肠痉挛、过敏性休克等症状。应用能干扰过敏介质释放的药物,就有可能减轻速发型变态反应的症状,达到治疗目的。已有药物中如色甘酸钠就具有这方面的作用。近发现一些中草药也有此作用。本文仅将影响速发型变态反应的中草药作一综述。对速发型变态反应过敏介质释放有影响的中草药江田等曾对31种中草药的水及乙醇提取物进行实验,发现使总过敏介质释放量减少40%以上的有枳实、防己的水提取物以及枳实,麻黄、细辛的乙醇提取物;减少20～40%的有牛膝、细辛、桂皮、麻黄、牛胆和辛夷的水提取物以及丹皮、桃仁的乙醇提取物。使过敏介质释放量增加40%以上的有柴胡的水提
In the case of rapid-onset allergic reaction (first-type allergic reaction), symptoms such as rash, dermatitis, urticaria, bronchial asthma, gastrointestinal spasm, and anaphylactic shock are caused due to the release of an allergic mediator. The use of drugs that can interfere with the release of allergic mediators, it is possible to reduce the symptoms of immediate-onset allergic reactions for therapeutic purposes. Existing drugs such as cromolyn sodium have this effect. Recently found that some Chinese herbal medicine also have this effect. This article will only affect the quick-onset allergy herbal made a review. On the hair allergic hypersensitivity hypersensitive mediator release of Chinese herbal medicine such as Jiang Tian et al had 31 kinds of Chinese herbal medicine water and ethanol extract was found to reduce the total allergic media release more than 40% of citrus aurantium, anti-mycophenolate extract and Citrus aurantium, ephedra, asarum ethanol extract; reduce 20 to 40% of Achyranthes, asarum, cinnamon, ephedra, gall and Magnolia water extract and Danpi, peach kernel ethanol extract. The allergic medium to increase the amount of more than 40% of Bupleurum water extraction