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目的观察匹多莫德对儿童反复呼吸道感染的临床疗效及免疫功能的影响。方法选取医院收治的反复呼吸道感染患儿119例,随机分为观察组60例和对照组59例。对照组采取常规治疗方法,观察组在对照组基础上给予匹多莫德口服治疗,比较2组的临床疗效,检测2组治疗后Ig G、Ig M水平。结果观察组痊愈率和总有效率分别为43.33%和91.67%,均高于对照组的30.51%和81.36%(P<0.05)。治疗后,观察组Ig G、Ig M水平均高于对照组(P<0.05)。结论采用匹多莫德治疗儿童反复呼吸道感染临床效果显著,患儿血清Ig G、Ig M水平较高,免疫功能提高,值得临床推广应用。
Objective To observe the effect of pidotimod on the clinical efficacy and immune function of children with recurrent respiratory tract infections. Methods A total of 119 children with recurrent respiratory tract infection admitted to hospital were randomly divided into observation group (60 cases) and control group (59 cases). The control group took the conventional treatment. The observation group was treated with Pidotimod on the basis of the control group. The clinical curative effect was compared between the two groups. The levels of Ig G and Ig M in the two groups were detected. Results The cure rate and total effective rate in the observation group were 43.33% and 91.67%, respectively, which were higher than those in the control group (30.51% and 81.36%, P <0.05). After treatment, the levels of Ig G and Ig M in the observation group were higher than those in the control group (P <0.05). Conclusion Pidotimod treatment of children with recurrent respiratory tract infections have significant clinical effects, serum Ig G, Ig M levels higher, immune function, worthy of clinical application.