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目的观察生脉注射液联合磷酸肌酸钠对冠心病心绞痛的临床疗效。方法将125例心绞痛患者随机分为两组(治疗组65例,对照组60例)。对照组在西医常规治疗基础上给予磷酸肌酸钠1g加入5%葡萄糖或0.9%生理盐水100m L静脉滴注,日2次;治疗组在对照组治疗基础上给予生脉注射液100m L静脉滴注,日1次。两组患者均连续用药2周,比较两组临床疗效。结果治疗组心绞痛总有效率92.31%,对照组总有效率83.3%,两组比较差异有统计学意义(P<0.05);心电图疗效比较:治疗组总有效率90.77%,对照组总有效率78.3%,两组比较差异有统计学意义(P<0.05)。治疗组治疗后心绞痛发作次数明显减少,持续时间明显缩短,组间比较差异有统计学意义(P<0.05)。结论生脉注射液联合磷酸肌酸对冠心病心绞痛疗效好,无明显毒副反应。
Objective To observe the clinical effect of Shengmai injection combined with creatine phosphate on angina pectoris of coronary heart disease. Methods 125 patients with angina pectoris were randomly divided into two groups (treatment group, 65 cases, control group, 60 cases). The control group was given intravenous drip of 1% sodium creatine phosphate 5% dextrose or 0.9% normal saline 100ml on the basis of routine treatment of Western medicine twice a day. The treatment group was given Shengmai injection 100ml intravenous drip on the basis of the control group Note, day 1. Two groups of patients were treated for 2 weeks, the clinical efficacy of two groups were compared. Results The total effective rate of angina pectoris in the treatment group was 92.31%, the total effective rate in the control group was 83.3%, the difference between the two groups was statistically significant (P <0.05). The comparison of the electrocardiogram curative effect: the total effective rate was 90.77% in the treatment group and 78.3% %, The difference between the two groups was statistically significant (P <0.05). After treatment, the number of angina attacks in treatment group decreased significantly, and the duration of treatment was significantly shortened. The difference between the two groups was statistically significant (P <0.05). Conclusion Shengmai injection combined with creatine phosphate on coronary heart disease angina pectoris good effect, no obvious side effects.