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目的研究橄榄油对自身免疫性睾丸炎睾丸组织结构及血清抑制素B和卵泡刺激素含量的影响,以探讨橄榄油对睾丸炎的组织结构的拮抗作用及机制。方法选择健康成熟雄性BALB/c小鼠30只,随机分3个组,正常对照组、模型组和橄榄油组,光镜观察睾丸生精小管内的变化,ELISA法检测血清抑制素B和卵泡刺激素的变化。结果橄榄油组睾丸系数、血清抑制素B和卵泡刺激素含量与模型组比较,差异有统计学意义(P<0.05),HE染色观察可见模型组小鼠生精小管内无生精细胞,橄榄油组小鼠生精小管内可以看到大量的生精细胞。结论橄榄油对自身免疫性睾丸炎炎症损伤具有一定的保护作用。
Objective To study the effect of olive oil on testis tissue structure, serum inhibin B and follicle stimulating hormone in autoimmune orchitis, and to explore the antagonistic effect and mechanism of olive oil on the histological structure of orchitis. Methods Thirty healthy male BALB / c mice were randomly divided into three groups: normal control group, model group and olive oil group. The changes of testicular seminiferous tubules were observed with light microscope. Serum inhibin B and follicles Stimulant changes. Results The testis coefficient, serum inhibin B and follicle stimulating hormone in the olive oil group were significantly different from those in the model group (P <0.05). HE staining showed no spermatogenic cells in the seminiferous tubules of the model group, Oil group of mice seminiferous tubules can see a large number of spermatogenic cells. Conclusion Olive oil has certain protective effect on autoimmune orchitis inflammation.