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目的评价肝动脉CO2DSA和CT血管造影(CO2CTA)在健康实验猪中的影像学表现。方法健康实验猪5头,全麻下经股动脉插管至肝固有动脉,先行碘对比剂肝动脉DSA(5ml/s,10ml),再手推CO230～50ml(5～8ml/s)行CO2DSA,然后再行CO2CTA。全麻下处死动物,选择性获取肝组织作病理学检查。分析比较碘对比剂DSA和CO2DSA和CO2CTA的图像表现特点,以及显示动静脉瘘的能力。结果碘对比剂肝动脉DSA未显示任何动静脉瘘,而CO2DSA显示3头猪在动脉晚期相气体进入门脉分支而使局部的段或叶门脉分支显影,并在CO2CTA上得到证实。门脉内气体在1～3min内吸收。CO2DSA和CO2CTA均未见CO2气体进入肝静脉。病理检查肝组织未见明显异常病理改变。结论(1)CO2DSA和CO2CTA显示健康实验猪肝动脉注射CO2后气体在动脉晚期相进入局部门脉分支,于1～3min内吸收消失。(2)健康实验猪CO2肝动脉灌注后CO2不会进入肝静脉。
Objective To evaluate the imaging findings of hepatic artery CO2DSA and CT angiography (CO2CTA) in healthy pigs. Methods Five healthy pigs underwent general anesthesia with hepatic artery DSA (5ml / s, 10ml) via cannulation of the femoral artery. The animals were treated with CO2DS 50 ~ 5ml (5 ~ 8ml / s) , Then re-CO2CTA. Animals were sacrificed under general anesthesia and liver tissues were selectively obtained for pathological examination. Analysis and comparison of iodine contrast agents DSA and CO2DSA and CO2CTA image performance characteristics, as well as the ability to display arteriovenous fistula. Results The iodine contrast agent did not show any arteriovenous fistula in the DSA of the hepatic artery, whereas CO2DSA showed that 3 pigs entered the portal vein branch in the late phase of arterial phase to develop local segmental or mesenteric branches and was confirmed on CO2CTA. Portal gas within 1 ~ 3min absorption. No CO2 gas was found in the hepatic veins between CO2DSA and CO2CTA. Pathological examination of liver tissue showed no obvious pathological changes. Conclusions (1) CO2DSA and CO2CTA show that after experimental injection of CO2 into porcine hepatic artery, the gas enters the branch of the portal vein in the late arterial phase and disappears within 1 ~ 3min. (2) CO2 did not enter the hepatic vein after the healthy experimental pigs CO2 hepatic artery perfusion.