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目的:探讨脑卒中后继发Wallerian变性的磁共振表现及病变性质、病变部位与Wallerian变性的关系。方法:回顾性分析60例原发病变均位于幕上、单侧发病的脑血管病患者(脑梗死和脑出血各30例)临床及MRI资料,对继发锥体束Wallerian变性的MRI表现及原发病、病变部位与Wallerian变性的关系进行分析。结果:脑梗死组30例中16例出现Wallerian变性,脑出血组30例中5例出现Wallerian变性,两组比较差异有统计学意义(P<0.05)。结论:MRI是诊断Wallerian变性的可靠方法,脑梗死导致Wallerian变性的发生率高于脑出血;病变部位越靠近皮层锥体细胞,越易继发Wallerian变性;病变范围越大,出现Wallerian变性的机会越多。
Objective: To investigate the magnetic resonance imaging (MRI) of secondary Wallerian degeneration after stroke and its relationship with the nature of the lesion, the lesion and Wallerian degeneration. Methods: The clinical data and MRI data of 60 patients with cerebrovascular disease (30 patients with cerebral infarction and cerebral hemorrhage) who were all on the infratentorial and unilateral disease were retrospectively analyzed. The MRI findings of Wallerian degeneration were analyzed. Primary disease, lesions and Wallerian degeneration of the relationship analysis. Results: Wallerian degeneration was found in 16 out of 30 cases in cerebral infarction group and Wallerian degeneration in 5 out of 30 cases in cerebral hemorrhage group. There was significant difference between the two groups (P <0.05). Conclusion: MRI is a reliable method to diagnose Wallerian degeneration. The incidence of Wallerian degeneration is higher than that of intracerebral hemorrhage. The closer the lesions are to the cortical pyramidal cells, the more prone to Wallerian degeneration. The larger the lesion, the more chance of Wallerian degeneration more.