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目的探讨脑卒中发病与气象条件的关系。方法脑梗塞与脑出血病的病例由日本广岛市急救中心于2003年10月~2006年3月收集,气象数据由日本气象协会提供。日平均气温和气压分别定义为分组变量,采用泊松回归分析模型估计不同气温和气压条件下脑梗塞与脑出血发病的危险度。结果在研究的892 d中,发生脑梗塞629例(男性占56.9%,女性占436.1%);发生脑出血677例(男性占55.7%,女性占44.3%)。脑梗塞发病与气温呈U字形的关系,发病的危险度在21~24℃时最低,当气温低于15℃和高于30℃时,发病的危险度升高(P<0.05);脑梗塞发病的危险度在日平均气压高于1 015hPa时增大(P<0.05)。脑出血发病的危险度随气温的升高而减小(P<0.05),随气压的升高而增大(P<0.05),并呈剂量-反应关系。结论脑梗塞和脑出血的发病与气温、气压有关。
Objective To explore the relationship between stroke incidence and meteorological conditions. Methods The cases of cerebral infarction and cerebral hemorrhage were collected by the Hiroshima Emergency Center in Japan from October 2003 to March 2006 and the meteorological data were provided by the Japan Meteorological Association. Daily average temperature and pressure were defined as group variables, and Poisson regression analysis models were used to estimate the risk of cerebral infarction and cerebral hemorrhage at different temperatures and pressures. Results In 892 d of the study, 629 cerebral infarctions occurred (56.9% for males and 436.1% for females); 677 (67.5% for men and 44.3% for females) developed cerebral hemorrhage. The incidence of cerebral infarction and the temperature was U-shaped relationship, the risk of onset in the lowest 21 ~ 24 ℃, when the temperature is below 15 ℃ and higher than 30 ℃, the risk of onset increased (P <0.05); cerebral infarction The risk of onset increased when the mean daily air pressure was higher than 1 015 hPa (P <0.05). The risk of cerebral hemorrhage decreased with the increase of temperature (P <0.05), increased with the increase of barometric pressure (P <0.05), and showed a dose-response relationship. Conclusion The incidence of cerebral infarction and cerebral hemorrhage is related to temperature and pressure.