前列腺癌的基因治疗是当前的研究热点,但基因治疗真正应用于临床必须有良好的肿瘤选择性(靶向性)。本文在前列腺癌基因治疗的转染、表达、靶向特异性基因等几个层面以及不同的基因载体的靶向前列腺癌策略进展加以综述,为前列腺癌基因治疗的靶向设计提供参考。 Gene therapy of prostate cancer is the current research focus, but the true application of gene therapy in clinical must have good tumor selectivity (targeting). This review summarizes the progress of strategies targeting prostate cancer at several aspects of transfection, expression, targeted specific genes and other gene vectors for prostate cancer gene therapy, and provides a reference for the targeted design of gene therapy for prostate cancer.