既往研究表明,长效β_2受体兴奋剂Salmeterol(沙美特罗)、Formoterol(福莫特罗)作用至少持续12h以上,单一应用可影响气道口径和气道反应性的昼夜节律变化。本文观察单剂Salmeterol和Formoterol对轻型哮喘24h的作用。 12例未用过激素、茶碱、色甘酸钠、nedocroml及长效β_2受体兴奋剂的轻型哮喘患者,平均年龄24岁(19～31岁),进行随机双盲对照试验,测定肺功能FEV作为基线标准后,用定量吸入器随机分别吸入安慰剂、 Previous studies have shown that long-acting β 2 receptor agonists Salmeterol and Formoterol lasts for at least 12 hours, and the single application may affect the circadian rhythm of airway caliber and airway responsiveness. This article observed a single dose of Salmeterol and Formoterol on the role of light-induced asthma 24h. Twelve patients with mild asthma who did not use hormones, theophylline, cromolyn, nedocroml and long-acting β_2 receptor agonist were 24 years old (19 to 31 years old) with randomized, double-blind controlled trials and their pulmonary function FEV As a baseline standard, placebo was inhaled randomly with a metered-dose inhaler,