与肽类激素和固醇类激素相比,研究甲状腺激素的神经作用是很少的。长时期以来多认为甲状腺素在成年脑内不引起能量代谢的变化,同时成熟脑对甲状腺素也不再发生反应。因此对于在大多数甲亢或甲低病人身上看到的行为和精神症状,多被认为是甲状腺机能紊乱对外周作用的继发性中枢变化。另外,对于甲状腺机能紊乱表现的植物神经功能的失调,被认为是甲状腺素引起外周效应器上β肾上腺能受体的超敏作用的结果,即外周组织的β受体数目和功能随甲状腺素的增加而增加,其结果是改变了效应器官的反应性。 但近年来有人开始重视甲状腺素作为原 Compared with peptide hormones and steroid hormones, thyroid hormones to study the role of nerves is very small. More long believed that thyroxine in the adult brain does not cause changes in energy metabolism, while mature brain thyroxine no longer react. Therefore, for the majority of hyperthyroidism or hypothyroidism seen in patients with behavioral and psychiatric symptoms, many are considered to be the role of thyroid disorders secondary to peripheral effects of central changes. In addition, dysfunction of the autonomic function of thyroid dysfunction is considered to be the result of thyroid hormone-induced hypersensitivity of beta adrenergic receptors on the peripheral effector, ie, the number and function of beta receptors in peripheral tissues varies with thyroid hormone Increases and increases, the result is to change the responsiveness of the effector. However, in recent years, some people have begun to value thyroxine as the original