为了解非典型抗精神病药物引起锥体外系症状(EPS)的情况,利用Medline检索系统对已公开发表的临床随机对照试验与流行病学资料进行分析。非典型抗精神病药物间引起EPS的程度各有差异,有的与剂量相关,总体较经典的抗精神病药物发生率低,严重程度轻。但临床仍应重视锥体外系症状的预防与治疗问题。 To understand the extrapyramidal symptoms (EPS) caused by atypical antipsychotics, published clinical randomized controlled trials and epidemiological data were analyzed using the Medline search system. Atypical antipsychotic drugs cause EPS levels vary, and some dose-related, the overall lower than the classic antipsychotics, the severity of light. However, the clinical should still attach importance to the prevention and treatment of extrapyramidal symptoms.