论文部分内容阅读
本研究采用卵蛋白等致敏大鼠哮喘模型,观察正常组、哮喘组和中药治疗组大鼠血清中总IgE、白细胞介素-4和γ-干扰素的含量变化。结果表明:哮喘大鼠血清总 IgE水平、IL-4含量明显增加(P <0.01),血清中 IFN-γ含量明显降低(P<0.01),而补脾益气方药可显著降低哮喘大鼠 IgE水平及IL-4含量(P<0.01),提高IFN-γ的含量(P<0.01)。
In this study, sensitized rat asthma models such as ovalbumin were used to observe the changes of serum total IgE, interleukin-4, and interferon-gamma in normal, asthma, and Chinese medicine-treated groups. The results showed that serum levels of total IgE and IL-4 were significantly increased in asthmatic rats (P <0.01), serum IFN-γ levels were significantly decreased (P <0.01), and Spleen and Yiqi prescriptions were significantly reduced. IgE levels and IL-4 levels in asthmatic rats (P<0.01) increased IFN-γ levels (P<0.01).