很多研究提示肠道粘膜屏障不全可能是细菌移位(BT)过程的开始。最近研究发现,一氧化氮(NO)在调节BT或感染中有矛盾的双重作用,它有直接的杀菌作用,也可间接地通过扩张血管、增加局部血流量而促进杀菌作用,但持久的NO释放也可导致细胞损害和肠道粘膜屏障不全,促进细菌移位。本研究在SD大鼠背部 Many studies suggest that incomplete intestinal mucosal barrier may be the beginning of the bacterial translocation (BT) process. Recent studies have found that nitric oxide (NO) has a contradictory dual role in the regulation of BT or infection. It has a direct bactericidal effect and can indirectly promote the bactericidal effect by dilating blood vessels and increasing local blood flow. However, persistent nitric oxide Release can also lead to cellular damage and intestinal mucosal barrier insufficiency, promoting bacterial translocation. This study was performed on the back of SD rats