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１．材料与方法：取Ｗｉｓｔａｒ雄性大鼠２０只，体重２２０ ～２５０ｇ，随机分为对照组及实验组。采用本室已建立的复合因素致病法复制肝硬化模型。于实验第九周末处死动物，取部分肝脏置１０％的甲醛溶液内固定、石蜡包埋、常规组织制片，免疫组织化学方法检测肝组织中内
1. MATERIALS AND METHODS: Twenty Wistar male rats weighing 220-250 g were randomly divided into control group and experimental group. Using this room has been established compound pathogenic replication of cirrhosis model. Animals were killed at the end of the ninth week of experiment. Some of the liver was fixed in formaldehyde solution of 10%, paraffin embedded, routine tissue preparation and immunohistochemistry