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虽说乳腺癌可以只通过局部治疗而痊愈,但一般认为,对绝大多数病例进行一些辅助性治疗还是必要的。手术的目是为了除去癌肿,但亦有可能导致癌细胞栓子的扩散。如果在组织活检或乳腺切除过程中,具有生物活性的肿瘤栓子扩散到有高浓度催乳素存在的环境中,将加速瘤细胞的生长。已经知道,催乳素是乳腺内皮生长的促进剂。在对乳腺癌患者行外科手术时,由于应激反应可引起催乳素的血液浓度持续升高。催乳素浓度升高与乳腺癌的不良预后有很密切的关系。通过降低血浆催乳素浓度从而抑制微小转移的肿瘤细胞的生长率是很
Although breast cancer can be cured only by topical treatment, it is generally believed that it is necessary to perform some supplementary treatments for most cases. The purpose of surgery is to remove cancer, but it may also lead to the proliferation of cancerous emboli. If bioactive tumor emboli diffuses into the presence of a high concentration of prolactin during tissue biopsy or mastectomy, the growth of the tumor cells will be accelerated. It is known that prolactin is a promoter of breast endothelium growth. In surgery for breast cancer patients, prolonged blood levels of prolactin can be caused by stress reactions. Prolactin concentration is closely related to the poor prognosis of breast cancer. By reducing plasma prolactin concentration, the growth rate of tumor cells that inhibit micrometastases is very high