4-氨基丁醇是化学合成较常用的一种原料。其制备方法较多,实验室常用Gabriel合成法,但收率较低,其合成过程如下: 我们对中间体4-(邻苯二甲酰亚胺基)丁基醋酸酯(2)的合成作了改进,将成盐和取代反应于同一反应器内完成,同时间歇地除去反应系统中产生的水。通过优化试验,使收率提高至 4-Aminobutanol is a more commonly used chemical synthesis of a raw material. The preparation method is more commonly used in laboratories Gabriel synthesis, but the yield is low, the synthesis process is as follows: We intermediate 4- (phthalimide) butyl acetate (2) for the synthesis Improvements are accomplished by salt-forming and substituting reactions in the same reactor while intermittently removing the water produced in the reaction system. By optimizing the test, the yield was increased to